| Autor: |
Rossi, Alice, Cattabriga, Arrigo, Bezzi, Davide |
| Zdroj: |
PET Clinics; 20240101, Issue: Preprints |
| Abstrakt: |
According to international guidelines, patients with suspected myeloma should primarily undergo low-dose Whole Body Computed Tomography for diagnostic purposes. To optimize sensitivity and specificity and enable treatment response assessment, Whole Body Magnetic Resonance Imaging (WB-MRI) should include Diffusion Weighted Imaging with Apparent Diffusion Coefficient maps and T1-weighted Dixon sequences with bone marrow Fat Fraction quantification. At baseline WB-MRI shows greater sensitivity for the detecting focal lesions and diffuse bone marrow infiltration pattern than18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography (PET-CT), which is considered of choice for evaluating response to treatment and minimal residual disease and imaging of extramedullary disease (EMD). Both WB-MRI and PET-CT findings have been associated with patient's prognosis. Due to tumor heterogeneity and new therapies, the most current research indicates that PET-CT and WB-MRI may play complimentary roles in providing distinct and complementary information. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
|
