Autor: |
Jostes, Sina, Vardabasso, Chiara, Dong, Joanna, Carcamo, Saul, Singh, Rajendra, Phelps, Robert, Meadows, Austin, Grossi, Elena, Hasson, Dan, Bernstein, Emily |
Zdroj: |
Genes & Development; 2024, Vol. 38 Issue: 7-8 p336-353, 18p |
Abstrakt: |
In this study, Jostes et al. describe the essential role for H2A.Z histone chaperones SCRAP, p400, and YL1 in regulating H2A.Z deposition and H4 acetylation on chromatin in melanoma cells. Their findings demonstrate that the chaperones coordinate expression of E2F1 and its targets, thereby highlighting a new epigenetic strategy for cancer intervention. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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