Efficacy and safety of three antiretroviral therapy regimens for treatment-naive African adults living with HIV-2 (FIT-2): a pilot, phase 2, non-comparative, open-label, randomised controlled trial

Autor: Eholie, Serge P, Ekouevi, Didier K, Chazallon, Corine, Charpentier, Charlotte, Messou, Eugène, Diallo, Zelica, Zoungrana, Jacques, Minga, Albert, Ngom Gueye, Ndeye Fatou, Hawerlander, Denise, Dembele, Fassery, Colin, Géraldine, Tchounga, Boris, Karcher, Sophie, Le Carrou, Jérome, Tchabert-Guié, Annick, Toni, Thomas-d'Aquin, Ouédraogo, Abdoul-Salam, Bado, Guillaume, Toure Kane, Coumba, Seydi, Moussa, Poda, Armel, Mensah, Ephrem, Diallo, Illah, Drabo, Youssouf Joseph, Anglaret, Xavier, Brun-Vezinet, Françoise, Anglaret, Xavier, Assoumou, Lambert, Bado, Guillaume, Bissagnene, Emmanuel, Bonnet, Fabrice, Britto, Carlos, Brun Vezinet, Françoise, Charpentier, Charlotte, Chazallon, Corine, Chenal, Henri, Chêne, Geneviève, Chenier, Remy, Clouet, Gwenaelle, Colin, Géraldine, Collin, Gilles, Conte, Valérie, Danel, Christine, De Monteynard, Laure-Amélie, Dembele, Fassery, Diallo, Zelica, Diallo, Illah, Dohoun, Lambert, Drabo, Youssouf Joseph, Eholié, Serge Paul, Ekouevi, Didier Koumavi, Fadiga, Fatoumata, Gabillard, Delphine, Girard, Pierre Marie, Gottlieb, Geoffrey S., Hawerlander, Denise, Karcher, Sophie, Kariyiare, Benjamin, Koita Fall, Mame Basty, Konan, Romuald, Kouame, Antoine, Kouley, Serge-Olivier, Laborde Bolen, Gabriele, Landman, Roland, Le Carrou, Jérome, Marcelain, Anne Geneviève, Matheron, Sophie, Mensah, Ephrem, Mercier, Noémie, Messou, Assoua, Messou, Eugène, Minga, Albert, N'dour, Cheick Tidiane, N'chot, Celestin, Ndiaye, Bara, Ngom Gueye, Ndeye Fatou, N'guessan-Koffi, Larissa, Ouattara, Eric, Ouédraogo, Abdoul-Salam, Palokinam Pitche, Vincent, Peytavin, Gilles, Plantier, Jean Christophe, Poda, Armel, Prince-David, Mireille, Raffali, Yasmine, Rekacewicz, Claire, Rouzioux, Christine, Salou, Mounerou, Sangare, Lassana, Sawadogo, Adrien Bruno, Seydi, Moussa, Somé, Désiré, Tamegnon, Séphora, Tchabert-Guié, Annick, Tchounga, Boris, Toni, Thomas d'Aquin, Toure Kane, Coumba, Touret, Pierre, Traoré, Jean-Richard, Vitoria de Avila, Marco Antonio, Yaméogo, Seydou, Yao Yapi, Cyrille, Zoungrana, Jacques
Zdroj: The Lancet HIV; June 2024, Vol. 11 Issue: 6 pe380-e388, 9p
Abstrakt: Due to the low number of individuals with HIV-2, no randomised trials of HIV-2 treatment have ever been done. We hypothesised that a non-comparative study describing the outcomes of several antiretroviral therapy (ART) regimens in parallel groups would improve understanding of how differences between HIV-1 and HIV-2 might lead to different therapeutic approaches.
Databáze: Supplemental Index