| Autor: |
Hata-Tanaka, Akiko, Kita, Kiyoshi, Furushima, Rieko, Oya, Hiroshi, Itoh, Shigeru |
| Zdroj: |
FEBS Letters; January 1988, Vol. 242 Issue: 1 p183-186, 4p |
| Abstrakt: |
Complex II of Ascaris suummitochondria, which functions as fumarate reductase in physiological conditions, contains three types of iron-sulfur clusters. These correspond to clusters S-1, S-2 and S-3 and are distinguishable by low-temperature ESR studies. Cluster S-1 is reduced by succinate, giving ESR signals with gz, gyand gxvalues at 2.033, 1.939 and 1.920. The existence of cluster S-2 is suggested by an enhancement of the S-1 spin relaxation induced upon reduction of S-2 by dithionite. Cluster S-3 is ESR detectable under air-oxidized conditions and gives a strong signal at g= 2.025. Cluster S-3 was only partially reduced even with an excess amount of sodium succinate, which is a common characteristic of fumarate reductase but this is not seen in the mitochondrial complex II. |
| Databáze: |
Supplemental Index |
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