The role of lipid peroxidation products in cumene hydroperoxide-induced Ca 2+efflux from mitochondria

Autor: Gogvadze, V.G., Zhukova, A.A.
Zdroj: FEBS Letters; January 1991, Vol. 287 Issue: 1 p139-141, 3p
Abstrakt: Cumene hydroperoxide-induced calcium release from mitochondria has been studied. Activation of lipid peroxidation by increasing concentrations of cumene hydroperoxide does not enhance calcium efflux induced by low (up to 50 μM) concentration of cumene hydroperoxide. It is concluded that cumene hydroperoxide-induced calcium release depends mainly on processes coupled to hydroperoxide reduction by an endogenous enzyme system.
Databáze: Supplemental Index