The L7/L12 proteins change their conformation upon interaction of EF-G with ribosomes

Autor: Gudkov, A.T., Gongadze, G.M.
Zdroj: FEBS Letters; January 1984, Vol. 176 Issue: 1 p32-36, 5p
Abstrakt: The different functional complexes of ribosomes with elongation factor F (EF-G) were studied by digestion experiments with trypsin. It was found that upon interaction of EF-G with ribosomes the L7/L12 proteins are sensitive to trypsin and are trypsin resistant after dissociation of EF-G from ribosomes. The significance of conformational alterations in the L7/L12 and also in the other proteins in the translation process is discussed.
Databáze: Supplemental Index