| Autor: |
Penketh, P.G., Kennedy, W.P.K., Patton, C.L., Sartorelli, A.C. |
| Zdroj: |
FEBS Letters; January 1987, Vol. 221 Issue: 2 p427-431, 5p |
| Abstrakt: |
The rate of whole cell H 2O 2metabolism in several salivarian and stercorarian trypanosomes and Leishmaniaspecies was measured. These cells metabolized H 2O 2at rates between 2.3 and 48.2 nmol/10 8cells per min depending upon the species employed. H 2O 2metabolism was largely insensitive to NaN 3, implying that typical catalase and peroxidase haemoproteins are not important in H 2O 2metabolism. The metabolism of H 2O 2, however, was almost completely inhibited by N-ethylmaleimide. In representative species, H 2O 2metabolism was shown to occur through a trypanothione-dependent mechanism. |
| Databáze: |
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