Autor: |
Dibrov, P.A., Skulachev, V.P., Sokolov, M.V., Verkhovskaya, M.L. |
Zdroj: |
FEBS Letters; January 1988, Vol. 233 Issue: 2 p355-358, 4p |
Abstrakt: |
Subcellular vesicles of Vibrio alginolyticushydrolyse ATP and accumulate Na +in an ATP-dependent fashion. The Na +uptake is (i) strongly stimulated by Δψ-discharging agents, i.e., the protonophorous uncoupler CCCP or valinomycin +K +and (ii) arrested by DCCD at a concentration strongly inhibiting ATP hydrolysis. Lower concentrations of DCCD stimulate the Na +accumulation supported by ATP hydrolysis as well as by NADH oxidation. It is concluded that there is an electrogenic DCCD-sensitive Na +-ATPase in the cytoplasmic membrane of V. alginolyticus. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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