The H +/O ratio of proton translocation linked to the oxidation of succinate by mitochondria

Autor: Krab, Klaas, Soos, Jozsef, Wikström, Mårten
Zdroj: FEBS Letters; January 1984, Vol. 178 Issue: 2 p187-192, 6p
Abstrakt: In a recent communication Lehninger and co-workers (Costa L.E., Reynaferje B., and Lehninger A.L. (1984) J. Biol. Chem. 259, 4802-4811) reported values approaching 8 for the H +/O ratio of vectorial proton ejection from rat liver mitochondria respiring with succinate. Here we present a rigorous analysis of these measurements which reveals that they may significantly overestimate the true H +/O stoicheiometry.
Databáze: Supplemental Index