Bacillus thuringiensistoxin inhibits K +-gradient-dependent amino acid transport across the brush border membrane of Pieris brassicaemidgut cells

Autor: Sacchi, V.Franca, Parenti, Paolo, Hanozet, Giorgio M., Giordana, Barbara, Lüthy, Peter, Wolfersberger, Michael G.
Zdroj: FEBS Letters; January 1986, Vol. 204 Issue: 2 p213-218, 6p
Abstrakt: The luminal membrane of larval midgut cells is the site of action of insecticidal delta-endotoxin from Bacillus thuringiensis. At concentrations that correspond to normal effective doses in vivo, the toxin inhibits the uptake of amino acids by brush border membrane vesicles prepared from midguts of Pieris brassicaelarvae. The toxin does not interact with the K +-amino acid symport but rather increases the K +permeability of the membrane. The toxin does not increase the permeability of lepidopteran midgut brush border membrane to either Na +or H +nor does it increase the K +permeability of brush border membrane vesicles prepared from mammalian small intestine,
Databáze: Supplemental Index