NADPH:O 2oxidoreductase of human eosinophils in the cell-free system

Autor: Bolscher, Ben G.J.M., Koenderman, Leo, Tool, Anton T.J., Stokman, Petra M., Roos, Dirk
Zdroj: FEBS Letters; January 1990, Vol. 268 Issue: 1 p269-273, 5p
Abstrakt: The NADPH oxidase of human eosinophils, measured in the cell-free system, shows the same characteristics as the enzyme from human neutrophils. All proteins required for activity of the enzyme are expressed in eosinophils at a higher level than in neutrophils. Eosinophils isolated from patients with chronic granulomatous disease show the same molecular defects as the neutrophils fom these patients.
Databáze: Supplemental Index