| Autor: |
Koizumi, Shinichi, Ryazanov, Alexey, Hama, Tokiko, Chen, Hao-Chia, Guroff, Gordon |
| Zdroj: |
FEBS Letters; January 1989, Vol. 253 Issue: 1 p55-58, 4p |
| Abstrakt: |
The nerve growth factor-sensitive phosphoprotein from PC12 cells, previously designated Nsp100, has been shown to be elongation factor 2 (EF-2). The criteria used for this identification include: (i) similarity of N-terminal sequence; (ii) phosphorylation by the same kinase; (iii) ADP-ribosylation mediated by diphtheria toxin; (iv) comparable function in cell-free protein synthesis. According to these criteria, Nsp 100 and EF-2 are identical and the kinase that phosphorylates Nsp100 in PC12 cells is calcium/calmodulin kinase III. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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