Autor: |
van den Bogert, C., Holtrop, M., de Vries, H., Kroon, A.M. |
Zdroj: |
FEBS Letters; January 1985, Vol. 192 Issue: 2 p225-229, 5p |
Abstrakt: |
Specific inhibition of mitochondrial protein synthesis reduces the oxidation rate of NADH-linked substrates in rat liver as well as in Neurospora crassamitochondria. The present study shows that this is due to the fact that inhibition of mitochondrial protein synthesis leads to a decrease of the concentration of active complex I. Therefore, these results demonstrate that at least one of the genes for the subunits of complex I is localized on mitochondrial DNA. |
Databáze: |
Supplemental Index |
Externí odkaz: |
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