| Autor: |
Harano, Teruo, Harano, Keiko, Shibata, Susumu, Ueda, Satoshi, Mori, Hiroo, Arimasa, Naomichi |
| Zdroj: |
FEBS Letters; January 1983, Vol. 156 Issue: 1 p20-22, 3p |
| Abstrakt: |
A new ‘silent’ abnormal hemoglobin, Hb Okayama [β2 (NA 2) His → Gln], happened to be discovered in a diabetic Japanese female living in Okayama Prefecture, Japan, in the course of glyco-Hb measurement of the blood samples of diabetic patients. This variant did not differ from Hb A by conventional electrophoretic tests. Only the isoelectric focusing on PAG plate for the determination of glyco-Hb and the cation exchanger chromatography were successful in the separation of this abnormal variant from Hb A and glyco-Hb. Functional study of the whole blood demonstrated a slight increase of oxygen affinity. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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