| Autor: |
Docampo, Roberto, Casellas, Angela M., Madeira, Eliana D., Cardoni, Rita L., Moreno, Silvia N.J., Mason, Ronald P. |
| Zdroj: |
FEBS Letters; January 1983, Vol. 155 Issue: 1 p25-30, 6p |
| Abstrakt: |
This study provides biochemical and electron spin resonance spectroscopic evidence that contract of human polymorphonuclear leukocytes with antibody-coated Trypanosoma cruzitriggers the respiratory burst. Oxygen consumption, superoxide anion and hydrogen peroxide release were stimulated under conditions of polymorphonuclear leukocyte-mediated killing. This stimulation did not occur under non-killing conditions when antibody was omitted. A common mechanism of cytotoxicity of human polymorphonuclear leukocytes against different T. cruziforms is suggested by the triggering of the respiratory burst by antibody-coated epimastigotes and trypomastigotes. |
| Databáze: |
Supplemental Index |
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