Steady-State Characterization of Systems with Moiety-Conservations Made Easy: Matrix Equations of Metabolic Control Analysis and Biochemical System Theory

Autor:	Cascante, Marta, Puigjaner, Joaquim, Kholodenko, Boris
Zdroj:	Journal of Theoretical Biology; January 7, 1996, Vol. 178 Issue: 1 p1-6, 6p
Abstrakt:	A set of matrix equations based on the Sensitivity Theory is derived that allows the expression of the global control properties of a pathway as a function of its local properties (and vice versa) by a single matrix inversion. The matrix of the local properties is built up from: (1) the experimentally determined coefficients, (2) a link matrix (which corresponds to the moiety-conservation relationships) and (3) the matrix reflecting the structural properties of the pathway.
Databáze:	Supplemental Index
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