| Autor: |
Akhrem, A.A., Kisel, M.A., Kozlov, I.A., Tsybovsky, I.S., Vulfson, E.N. |
| Zdroj: |
FEBS Letters; January 1985, Vol. 187 Issue: 2 p249-252, 4p |
| Abstrakt: |
1,5-Difluoro-2,4-dinitrobenzene completely inhibits F 1-ATPase when it is used at micromolar concentrations and the inhibitor/enzyme molar ratio is equal to 3. The inhibition can be reversed by dithiothreitol treatment. 7-Chloro-4-nitrobenzofurazan treatment of F 1-ATPase does not prevent the reaction of the enzyme with 1,5-difluoro-2,4-dinitrobenzene. The 1,5-difluoro-2,4-dinitrobenzene-induced inhibition is thought to be a result of the modification of a tyrosine residue with p K9.1. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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