| Autor: |
Tatemoto, Kazuhiko, Jörnvall, Hans, Siimesmaa, Sirkka, Halldén, Gunnel, Mutt, Viktor |
| Zdroj: |
FEBS Letters; January 1984, Vol. 174 Issue: 2 p289-293, 5p |
| Abstrakt: |
A 58-residue peptide has been isolated from extracts of porcine brain and shown to be an N-terminally extended cholecystokinin (CCK). The amino acid sequence of this peptide is: Ala-Val-Gln-Lys-Val-Asp- Gly-Glu-Ser-Arg-Ala-His-Leu-Gly-Ala-Leu-Leu-Ala-Arg-Tyr-Ile-Gln-Gln-Ala-Arg-Lys-Ala-Pro-Ser-Gly- Arg-Val-Ser-Met-Ile-Lys-Asn-Leu-Gln-Ser-Leu-Asp-Pro-Ser-His-Arg-Ile-Ser-Asp-Arg-Asp-Tyr(SO 3)-Met- Gly-Trp-Met-Asp-Phe-NH 2. The peptide was found to induce contraction of the guinea-pig gallbladder, but the pattern of this action seemed to differ from those of CCK-8 and CCK-33. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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