| Autor: |
Yi, Li−Na, Zhao, Tao, Bu, Jinghan, Long, Jiedi, Yang, Qiang |
| Zdroj: |
Organic Letters; 20240101, Issue: Preprints |
| Abstrakt: |
In this report, we present the dual activation models for transient directing group-directed and amino-self-directed Pd-catalyzed α-aminophosphonate side-chain C(sp3)-H arylation. Both strategies showed facile, efficient, and single regioselectivity in the reaction between free α-aminophosphonates and aryl iodides. Furthermore, the modification of amino and late-stage functionalization of the C(sp3)-P bond from products indicates potential applications for α-aminophosphonates. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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