Autor: |
Ryu, Kee Suk, Shaikh, Kashan, Goluch, Edgar, Fan, Zhifang, LiuMicro, Chang, Laboratory, Nanotechnology, Urbana-Champaign, University of Illinois at, Wright, 208 North |
Zdroj: |
Lab on a Chip - Miniaturisation for Chemistry and Biology; 2004, Vol. 4 Issue: 6 p608-613, 6p |
Abstrakt: |
Previously, we reported a micro magnetic stir-bar mixer driven by an external rotating magnetic field and its rapid mixing performance in polydimethyl-siloxane PDMS channels. The PDMS piece with embedded fluid channels were manually aligned to a glass substrate and assembled. In this paper, we report the fabrication and testing results of a micro magnetic stir-bar monolithically integrated in parylene surface-micromachined channels with improved design features, including small tolerance of the stir-bar to channel wall 10 µm. Using of parylene based microchannels with improved design not only provides improved mixing, but also eliminates certain problems associated with PDMS-based channels. For example, porosity of PDMS causes evaporation and absorption of chemicals and thus channels made of PDMS are prone to cross-contamination. We have also demonstrated that the magnetic stir-bar can be used to pump liquid in micro channels. |
Databáze: |
Supplemental Index |
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