Tyrosinase, Elastase, Lipoxygenase Inhibition Activities and chemical composition of essential oils from Menthaspicata, Thymus vulgaris, Citrus aurantiumand Juniperusphoenicafrom Tunisia

Autor: Mhiri, Rania, Azoulay, Stephane, Fernandez, Xavier, Michel, Thomas, Allouche, Noureddine
Zdroj: Chemistry Africa; August 2024, Vol. 7 Issue: 6 p3059-3066, 8p
Abstrakt: Essential oils from four aromatic plants growing in Tunisia (Mentha spicata, Thymus vulgaris, Citrus aurantiumand Juniperus phoenica) were examined for their chemical composition and inhibitory properties against tyrosinase, lipoxygenase and elastase. These biological activities would make these aromatic plants as a valuable source for natural products useful in the cosmetic industry. Chemical composition was determined using gas chromatography coupled with mass spectrometry. The main identified constituents were pulegone (60.88%) in M. spicata, camphor (39.10%) in Thymus, artemisia ketone (20.09%) in C. aurantiumand linalool (36.73%) in J. phoenica. Essential oils from J. phoenicaand Thymus vulgarisexhibited a strong elastase inhibitory activity (IP = 80.43% and 45.56% respectively). Thymus vulgarisessential oil showed the greatest lipoxygenase inhibitory activity (IP = 100%), followed by J. phoenica(IP = 32.84%). Results from the present study suggested that essential oils extracted from J. phoenicaand T. vulgarisendowed with potent anti-elatase, anti-lipoxygenase and anti-tyrosinase proprieties may be potential candidates as ingredients in cosmetic and pharmaceutical preparations.
Databáze: Supplemental Index