The connection between Dr. Harold Griffith and Richard Gill: new insights into the history of curare use in anesthesia from previously unknown correspondence

Autor: Elsherbini, Noha, Backman, Steven B.
Zdroj: Canadian Journal of Anesthesia; 20240101, Issue: Preprints p1-8, 8p
Abstrakt: Dr. Harold R. Griffith and Richard C. Gill figure prominently in curare’s storied history. In 1938, Gill returned from an Amazon expedition with over 11 kg of curare. After scientists at E. R. Squibb & Sons identified a plant source (Chondrodendron tomentosum) and isolated a stable extract of uniform potency (marketed as Intocostrin), Griffith administered it in the operating room in 1942, showing its advantages and safety. In this article, we report correspondence between Griffith and Gill, heretofore not appreciated, after finding a letter from Gill to Griffith affixed to the inside back cover of a book contained in a private library.
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