Human herpesvirus 6 reactivation and disease are infrequent in chimeric antigen receptor T-cell therapy recipients

Autor: Kampouri, Eleftheria, Krantz, Elizabeth M., Xie, Hu, Ibrahimi, Sarah S., Kiem, Erika S., Sekhon, Mandeep K., Liang, Emily C., Cowan, Andrew J., Portuguese, Andrew, Green, Damian J., Albittar, Aya, Huang, Jennifer J., Gauthier, Jordan, Pérez-Osorio, Ailyn C., Jerome, Keith R., Zerr, Danielle M., Boeckh, Michael J., Hill, Joshua A.
Zdroj: Blood; August 2024, Vol. 144 Issue: 5 p490-495, 6p
Abstrakt: •HHV-6 reactivation in plasma occurred in 6% and possible HHV-6 encephalitis in 0.2% of patients within 12 weeks after CARTx.•HHV-6 reactivation and disease are infrequent after CARTx, and routine HHV-6 monitoring is not warranted.
Databáze: Supplemental Index