Essential oils of Thymus munbyanussubsp. coloratus: chemical variability and evaluation of biological activities

Autor: Benbelaïd, Fethi, Khadir, Abdelmounaїm, Rebai, Redouane, Mebarki, Salsabil, Benziane, Yacine, Bendahou, Mourad, Muselli, Alain
Zdroj: Journal of Essential Oil Bearing Plants; March 2024, Vol. 27 Issue: 2 p469-481, 13p
Abstrakt: AbstractThe chemical compositions of Thymus munbyanussubsp. coloratusessential oils, an endemic plant in north Africa, were investigated using gas chromatography with flame ionization detection and gas chromatography-mass spectrometry. The antioxidant activity of the studied essential oils was evaluated through 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2,20-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt (ABTS) free-radical scavenging assays. Disc diffusion method and minimal inhibitory concentration (MIC) determination were applied to investigate the antimicrobial activity of Thymus munbyanussubsp. coloratusessential oil against ten bacterial and fungus strains. Fifty-one compounds were identified accounting for 90.3-95.9% of the total amount. Camphor (04.09-25.92%) was the major component in the essential oils obtained from five localities, followed by myrcene (00.66-17.11%) in four stations, then borneol (07.37-38.96%) in the essential oil obtained from three samples. The chemical variability of Thymus munbyanussubsp. coloratusessential oils was studied using statistical analysis, in which we found a direct relationship between geo climatic conditions and their chemical compositions. Thymus munbyanussubsp. coloratusessential oils exhibited a good radical-scavenging activity with IC50values up to 0.250 ± 0.51 and 0.596 ± 0.15 (mg/mL) in reductive potential of ABTS and DPPH free radicals, respectively, and a significant antimicrobial activity against Gram positive bacteria and fungal species with MIC up to 0.66 ± 0.28 (mg/mL) against Aspergillus flavus.
Databáze: Supplemental Index