| Autor: |
Yang, LuLu, Wu, Jiale, Li, Yang, Tang, Yuhai, Li, Jing, Xu, Silong |
| Zdroj: |
Organic Letters; April 2024, Vol. 26 Issue: 15 p3208-3212, 5p |
| Abstrakt: |
Herein, we report a catalyst-free reaction of cyclobutanone oximes with chlorophosphines (R2PCl), which forms a fragile C═N–O–PR2species that undergoes N–O homolysis, fragmentation, and radical–radical coupling, leading to the formation of cyano-containing phosphine oxides in good yields. The reaction features an in situactivation of cyclobutanone oximes for radical generation, in which R2PCl plays a dual role as both an activator and a reactant. |
| Databáze: |
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