Differentiating Brown Tumor From Bone Metastasis in Parathyroid Cancer Using 18F-FDG PET and 99mTc-MIBI SPECT

Autor: Tsukamoto, Suzune, Kawabata, Kazuna, Kawamura, Hitomi, Takata, Kuniaki, Hosono, Makoto
Zdroj: Clinical Nuclear Medicine; May 2024, Vol. 49 Issue: 5 p444-446, 3p
Abstrakt: A 69-year-old woman presented with a right clavicle pain. CT revealed a pathological fracture of the right clavicle, multiple osteolytic lesions, and a left cervical mass. 18F-FDG PET/CT demonstrated a marked FDG uptake in the cervical mass and osteolytic lesions indicative of metastatic parathyroid cancer. 99mTc-MIBI SPECT/CT revealed either faint or no uptake in the osteolytic lesions. However, a histopathological analysis after a parathyroidectomy and right clavicle biopsy confirmed the diagnosis of parathyroid cancer and the presence of benign brown tumors secondary to hyperparathyroidism. Postoperative imaging showed sclerotic change and a decreased FDG uptake in the bone lesions.
Databáze: Supplemental Index