Yin Yang 1 regulates cohesin complex protein SMC3 in mouse hematopoietic stem cells

Autor: Lu, Zhanping, Wang, Yinghua, Assumpção, Anna L. F. V., Liu, Peng, Kopp, Audrey, Saka, Sahitya, Mcilwain, Sean J., Viny, Aaron D., Brand, Marjorie, Pan, Xuan
Zdroj: Blood Advances; 20240101, Issue: Preprints
Abstrakt: •YY1 co-occupies with SMC3 at a large cohort of promoters genome-wide and represses SMC3 expression in HSPCs.•Establish a distinct regulatory circuit of two chromatin structural factors and its impact on HSC quiescence and metabolism.
Databáze: Supplemental Index