| Autor: |
Felipe Fumero, Eloísa, Walter, Carolin, Frenz, Joris Maximillian, Seifert, Franca, Alla, Vijay, Henning, Thorben, Angenendt, Linus, Hartmann, Wolfgang, Wolf, Sebastian, Serve, Hubert, Oellerich, Thomas, Lenz, Georg, Müller-Tidow, Carsten, Schliemann, Christoph, Huber, Otmar, Dugas, Martin, Mann, Matthias, Jayavelu, Ashok Kumar, Mikesch, Jan-Henrik, Arteaga, Maria Francisca |
| Zdroj: |
Blood; 20240101, Issue: Preprints |
| Abstrakt: |
•The histone demethylase PHF8 is a master regulator of cell-intrinsic immune response in AML.•Pharmacologically induced PHF8 phosphorylation activates RNA sensors, triggering IFN-I response and offering potential for AML immunotherapy. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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