A multicenter study of supportive‐expressive group therapy for women with BRCA1/BRCA2 mutations

Autor: Esplen, Mary Jane, Hunter, Jon, Leszcz, Molyn, Warner, Ellen, Narod, Steven, Metcalfe, Kelly, Glendon, Gord, Butler, Kate, Liede, Alexander, Young, Mary Anne, Kieffer, Stephanie, DiProspero, Lisa, Irwin, Ellen, Wong, Jiahui
Zdroj: Cancer; November 2004, Vol. 101 Issue: 10 p2327-2340, 14p
Abstrakt: Women with a BRCA1/BRCA2 mutation experience significant challenges. These include decision‐making regarding surgical options and notification to offspring and family, along with a sense of isolation, which may lead to psychological and emotional distress. The current study developed, standardized, and conducted preliminary testing of a supportive‐expressive group therapy intervention designed to address these challenges.Seventy women with a BRCA1/BRCA2 mutation recruited from familial cancer risk clinics participated in 12 sessions of supportive‐expressive group therapy that lasted 6 months. Before and after measures of psychosocial functioning, knowledge, and surveillance/surgery activities were completed.Sixty‐seven women completed the intervention. Significant improvements were observed in psychosocial functioning: cancer worries (P = 0.005), anxiety (P = 0.033), and depression (P = 0.015). Knowledge level and surveillance levels were high at baseline and there were no significant changes postintervention. A significant number of women made decisions concerning prophylactic surgery (oophorectomy/mastectomy) during and after the intervention.The feasibility of a supportive‐expressive group for BRCA1/BRCA2 mutation carriers was demonstrated. Findings from the study are consistent with an effective intervention. However, further research is required using a randomized controlled study design. Cancer 2004. © 2004 American Cancer Society.
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