The Effect of the Porosity of Materials Based on Tricalcium Phosphate on the Behavior of Mesenchymal Stem Cells

Autor: Evdokimov, P. V., Kiseleva, A. K., Larionov, D. S., Novoseletskaya, E. S., Efimenko, A. Yu., Scherbakov, I. M., Shipunov, G. A., Dubrov, V. E., Putlayev, V. I.
Zdroj: Inorganic Materials: Applied Research; October 2023, Vol. 14 Issue: 5-6 p1285-1291, 7p
Abstrakt: Abstract: The behavior of primarily isolated human stromal cells including dermal fibroblasts and mesenchymal stem/stromal cells (MSCs) upon interaction with ceramic materials based on tricalcium phosphate (TCP) with different pore sizes is studied. The effect of the emulsifier on the rheological characteristics of photosensitive emulsions based on calcium phosphate is investigated. The dependence of the conditions of preparation of photosensitive emulsions on the pore size in ceramic materials based on Ca3(PO4)2is demonstrated. Studies of the biocompatibility of macroporous bioceramics upon cultivation of human stromal cells and effect of the samples of the material with different pore sizes on the in vitro transcriptional activity of MSCs are carried out.
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