| Autor: |
Yan, Zhengquan, Tang, Yulian, Zhang, Zhaoran, Feng, Jing, Hao, Junkai, Sun, Shuo, Li, Meng, Song, Yuguang, Dong, Wei, Hu, Lei |
| Zdroj: |
Analytical Chemistry; 20240101, Issue: Preprints |
| Abstrakt: |
To boost the enzyme-like activity, biological compatibility, and antiaggregation effect of noble-metal-based nanozymes, folic-acid-strengthened Ag–Ir quantum dots (FA@Ag–Ir QDs) were developed. Not only did FA@Ag–Ir QDs exhibit excellent synergistic-enhancement peroxidase-like activity, high stability, and low toxicity, but they could also promote the lateral root propagation of Arabidopsis thaliana. Especially, ultratrace cysteine or Hg2+could exclusively strengthen or deteriorate the inherent fluorescence property with an obvious “turn-on” or “turn-off” effect, and dopamine could alter the peroxidase-like activity with a clear hypochromic effect from blue to colorless. Under optimized conditions, FA@Ag–Ir QDs were successfully applied for the turn-on fluorescence imaging of cysteine or the stress response in cells and plant roots, the turn-off fluorescence monitoring of toxic Hg2+, or the visual detection of dopamine in aqueous, beverage, serum, or medical samples with low detection limits and satisfactory recoveries. The selective recognition mechanisms for FA@Ag–Ir QDs toward cysteine, Hg2+, and dopamine were illustrated. This work will offer insights into constructing some efficient nanozyme sensors for multichannel environmental analyses, especially for the prediagnosis of cysteine-related diseases or stress responses in organisms. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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