Total Syntheses of (+)-Cylindricines C−E and (−)-Lepadiformine through a Common Intermediate Derived from an aza-Prins Cyclization and Wharton's Rearrangement

Autor: Liu, J., Hsung, R. P., Peters, S. D.
Zdroj: Organic Letters; October 2004, Vol. 6 Issue: 22 p3989-3992, 4p
Abstrakt: Enantioselective total syntheses of (+)-cylindricines C−E and (−)-lepadiformine through a common tricyclic intermediate are described here. These syntheses are concise and feature an aza-Prins cyclization and a seldom-used Wharton rearrangement en route to the common intermediate.
Databáze: Supplemental Index