Validated spectrophotometric approach for the estimation of an antiepileptic drug: retigabine in pure form and pharmaceutical formulations utilizing N-Bromosuccinimide as an oxidant

Autor: Garoub, Mohannad M., Sheikh, Ragaa El, Mohamed, Sara G., Mahmoud, Moataz S., Allem, Ahmed F. Abdel, Sayed, Ahmed El, Ghazy, Ahmed A., Gomaa, Nessma M., Abdalla, Sameh, Salem, Osama M.A., Gouda, Ayman A.
Zdroj: Talanta Open; August 2024, Vol. 9 Issue: 1
Abstrakt: •A newly spectrophotometric approach have been developed for quantifying of retigabine in pharmaceutical formulations.•The developed technique employ N-bromosuccinimide (NBS) as an oxidizing agent and three dyes.•The concentration ranges of 0.5-12, 0.5-16, and 0.5-10 µg/ml using amaranth, methylene blue, and indigo carmine, respectively.•The accuracy and precision of the approaches have been assessed for both intra-day and inter-day measurements.
Databáze: Supplemental Index