| Autor: |
Iwodi, Cornelius, Gberikon, Grace M., Ogbonna, Innocent Okonkwo, Agada, Emmanuel O. |
| Zdroj: |
Brazilian Journal of Microbiology; March 2024, Vol. 55 Issue: 1 p447-454, 8p |
| Abstrakt: |
The aim of this study was to investigate multi-drug-resistant (MDR) Escherichia coliin urine of adult male patients with enlarged prostate. Three hundred and sixty-eight samples of urine and blood were collected. Escherichia coliwas isolated, purified, and identified and prostate-specific antigen (PSA) was determined. Multi-drug resistance test and specific drug resistance genes were assessed. Prevalence of Escherichia coliwas high (38.5%) in patients with PSA of 60–79 ng ml−1and 60% were MDR. The isolates showed highest resistance to tetracycline (53.3.0%) and least to cephalosporins (5%). They had intLand gyrAgenes, which are integron, and quinolone resistance genes and sul1and sul2which are sulphonamide resistance–associated genes. Levofloxacin, ertapenem, and Augmentin (100% susceptibilities) were considered choice drugs for treatment of Escherichia coliinfection in patients with elevated PSA. |
| Databáze: |
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