In vivo macrophage engineering as novel therapeutic strategy against liver metastasis
| Autor: | Laviron, Marie, Guilliams, Martin |
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| Zdroj: | Trends in Cancer; 20240101, Issue: Preprints |
| Abstrakt: | A recent study by Kerzel et al.reports a novel therapeutic strategy to engineer tumor-associated macrophages in vivoby inducing the expression of IFNα in these cells. This approach allows for better antigen-presentation and T cell activation, leading to controlled tumor growth in multiple murine models of liver metastasis. |
| Databáze: | Supplemental Index |
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