Autor: |
Mahendran, Shunmugiah, Sankaralingam, Subbiah, Sethupathi, Senthurpandian Muthuramalinga, Kathiresan, Durairaj, Muthumani, Mahalingam, Kousalya, Loganathan, Palpperumal, Selvam, Harinathan, Balasundaram |
Zdroj: |
Biomass Conversion and Biorefinery; January 2024, Vol. 14 Issue: 2 p2063-2069, 7p |
Abstrakt: |
The polyphenol compound is extracted from Sargassum tenerrimumwith various bioactivities including antibacterial and antioxidant activity and MTT assay for cell cytotoxicity. The total phenolic content was 69.12 ± 0.24%. The S. tenerrimumpolyphenol was found to phytochemical constituent’s presence of flavonoids, saponins, tannins, phenolics, alkaloids and steroid. The antibacterial activity of polyphenol presented significant inhibition against ten human pathogen bacterial cultures such as Proteus mirabilis, Klebsiella oxytoca, Escherichia coli, Bacillus cereus, Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa, Vibrio cholerae, Salmonella typhiand Bacillus subtilis. The in vitro antioxidant activity and MTT assay revealed that the polyphenol has anticancer activity against HeLa cells. The polyphenol compound was characterized through HPLC. |
Databáze: |
Supplemental Index |
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