Staphylococcus aureusinduces drug resistance in cancer T cells in Sézary syndrome

Autor: Vadivel, Chella Krishna, Willerslev-Olsen, Andreas, Namini, Martin R. J., Zeng, Ziao, Yan, Lang, Danielsen, Maria, Gluud, Maria, Pallesen, Emil M. H., Wojewoda, Karolina, Osmancevic, Amra, Hedebo, Signe, Chang, Yun-Tsan, Lindahl, Lise M., Koralov, Sergei B., Geskin, Larisa J., Bates, Susan E., Iversen, Lars, Litman, Thomas, Bech, Rikke, Wobser, Marion, Guenova, Emmanuella, Kamstrup, Maria R., Ødum, Niels, Buus, Terkild B.
Zdroj: Blood; 20240101, Issue: Preprints
Abstrakt: •Enterotoxins from S aureusbacteria induce drug resistance in primary malignant T cells in SS.•Targeting bacteria, their toxins, and downstream signaling pathways in malignant T cells abrogate the induction of drug resistance.
Databáze: Supplemental Index