Evaluation of Complement Activation on Cardiopulmonary Bypass and in Retransfused Oxygenator and Shed Mediastinal Blood

Autor: Walpoth, B.H., Nikles, M., Spaeth, P.J., Nydegger, U.E., Althaus, U., Walpoth, B.H., Nikles, M., Spaeth, P.J., Nydegger, U.E., Althaus, U.
Zdroj: Journal of Extra-Corporeal Technology; September 1991, Vol. 23 Issue: 3 p128-133, 6p
Abstrakt: Several methods of blood salvage are used in cardiac surgery. Our aim was to study, on the basis of complement activation, the quality of autologous blood products reinfused to the patient. Eleven patients with elective myocardial revascularisation were studied for: operative and cardiopulmonary bypass (CPB) data, hematology, blood chemistry and complement activation (C3a [des Arg] and terminal complement complex [TCC] or C5b-9 complex). Centrifugated oxygenator blood (COB) and shed mediastinal blood (SMB) samples were examined before reinfusion into the patient and the effect of this retransfusion on the systemic values.
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