| Autor: |
Sutton, Robin G., Salisbury, Meders M., Barrett, Richard K., Dillon, Virginia W., Spinale, Francis G., Dearing, James P., Sutton, Robin G., Salisbury, Meders M., Barrett, Richard K., Dillon, Virginia W., Spinale, Francis G., Dearing, James P. |
| Zdroj: |
Journal of Extra-Corporeal Technology; March 1988, Vol. 20 Issue: 1 p7-10, 4p |
| Abstrakt: |
Mixed venous oxygen content is commonly used to determine the adequacy of oxygenation during cardiopulmonary bypass (CPB). Due to the shift in the oxyhemoglobin disassociation curve during hypothermia, it is unknown whether PvO2or SvO2is the best indicator of adequate perfusion. The purpose of this study was to determine if there were any differences in blood flow, calculated base deficit, total fluids, hematocrit and oxygen consumption for dogs in the following two groups: PvO2between 35–45mmHg and SvO2between 65–75%. Blood flow was managed in fourteen animals randomly assigned to the PvO2and SvO2group during hypothermic CPB. PvO2management required significantly higher blood flows and total fluids (p<0.05). Hematocrit was significantly higher in the SvO2group (p<0.05). No differences were detected between the two techniques in base deficit or oxygen consumption (p>0.4). These results suggest that in the canine model SvO2monitoring during hypothermic CBP is a better indicator of tissue perfusion because of lower blood flows, fluid requirement, and higher hematocrits. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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