| Autor: |
Beckley, Philip D., Duffner, Brett D., Laribee, Julia A., O’Brien, William B., Wittenmyer, Barbara L., Beckley, Philip D., Duffner, Brett D., Laribee, Julia A., O’Brien, William B., Wittenmyer, Barbara L. |
| Zdroj: |
Journal of Extra-Corporeal Technology; June 1989, Vol. 21 Issue: 2 p52-55, 4p |
| Abstrakt: |
High velocity arterial blood re-entry during cardiopulmonary bypass is known to be associated with numerous potential deleterious effects. One of these may be endothelial cell stress with resulting intimal injury. Previous studies by others would suggest that endothelial cell injury of this type could result in long-term vascular disease. To test the hypothesis that arterial reentry during cardiopulmonary bypass will induce endothelial injury, six mongrel dogs were divided into three study pairs: control (no bypass), continuous (non-pulsatile) bypass, and pulsatile bypass. Evans blue dye was used as a marker of aortic endothelial cell injury. Following each experimental period, the aorta was removed en bloc and examined for Evans Blue Dye staining. Sections of aortic tissue were also examined histologically for cellular damage. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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