| Autor: |
Haigh, Mary V., Paterson, Edith |
| Zdroj: |
The British Journal of Radiology; March 1956, Vol. 29 Issue: 339 p148-157, 10p |
| Abstrakt: |
In the Rhesus monkey, the effects have been studied of different dose levels of X irradiation given at a single session. The data has yielded an LD50(30 days) of 570 ± 25 r and a time of death of 14·7 ± 2·2 days for those animals dying after irradiation in the LD50zone of doses.The symptomatology of the radiation syndrome in the monkey is described and is seen to conform to that of other mammals, differing only in the degree of prominence of certain symptoms. Late morbidity has been seen in two female but not in the two male animals which “survived” doses higher than LD50. In both, late loss of cellularity in the haemopoietic system was found, associated with monocytosis.Certain of the effects on the peripheral blood are not entirely due to radiation but to the experimental procedure. True radiation effects dependent on dose are seen to be related in the degree of depression of certain cells, in the duration of depression and in the hyperplasia which occurs during the recovery period.The prognostic value of symptoms and blood counts is discussed; only the behaviour of the reticulocytes was seen to give an indication of the survival of an individual, a good prognosis being indicated by a rise of reticulocytes during the second week. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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