Targeting IGF2BP3 enhances antileukemic effects of menin-MLL inhibition in MLL-AF4 leukemia
| Autor: | Lin, Tasha L., Jaiswal, Amit K., Ritter, Alexander J., Reppas, Jenna, Tran, Tiffany M., Neeb, Zachary T., Katzman, Sol, Thaxton, Michelle L., Cohen, Amanda, Sanford, Jeremy R., Rao, Dinesh S. |
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| Zdroj: | Blood Advances; 20230101, Issue: Preprints |
| Abstrakt: | •Knockdown of IGF2BP3 sensitizes MLL-AF4 leukemia to menin-MLL inhibition.•These data support the role of IGF2BP3 as an oncogenic amplifier in MLL-AF4 leukemogenesis and its therapeutic potential. |
| Databáze: | Supplemental Index |
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