| Autor: |
Sritharan, Thulasi, Salim, Angela A., Capon, Robert J. |
| Zdroj: |
Journal of Natural Products; December 2023, Vol. 86 Issue: 12 p2703-2709, 7p |
| Abstrakt: |
An integrated program of chemical profiling (GNPS) coupled with an expanded format 24-well-plate miniaturized cultivation profiling (MATRIX) utilizing traditional as well as grain/pulse and cereal media permitted rapid prioritization of Aspergillus terreusCMB-SWF012 as a source of unprecedented natural products. Scaled-up cultivation on rice and PDA yielded the rare tripeptides asterripeptides A–C (1–3), new indolo-sesquiterpene Michael adducts terreusides A and B (4and 5), and known precursors asterresin A (6) and (+)-giluterrin (7). Structures for 1–7were assigned by detailed spectroscopic and chemical analysis and biosynthetic considerations. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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