Pleiotropic attenuating effect of Ginkgo bilobaagainst isoprenaline-induced myocardial infarction via improving Bcl-2/mTOR/ERK1/2/Na+, K+-ATPase activities

Autor: Asiwe, Jerome Ndudi, Ojetola, Abodunrin Adebayo, Ekene, Nwoke Enekabokom, Osirim, Esthinsheen, Nnamudi, Anthony Chibuzor, Oritsemuelebi, Benjamin, Onuelu, Jackson Erozueme, Asiwe, Nicholas, Eruotor, Harrison Ogheneochuko, Inegbenehi, Saviour
Zdroj: Chinese Herbal Medicines; April 2024, Vol. 16 Issue: 2 p282-292, 11p
Abstrakt: Myocardial infarction (MI) is linked to an imbalance in the supply and demand of blood oxygen in the heart muscles. Beta-blockers and calcium antagonists are just two of the common medications used to treat MI. However, these have reportedly been shown to be either ineffective or to have undesirable side effects. Extract of Ginkgo bilobaleaves (GBE), a Chinese herbal product offers special compatibility benefits in therapeutic settings relating to inflammatory diseases and oxidative stress. In order to better understand how GBE affects MI in rats insulted by isoprenaline (ISO), the current study was designed.
Databáze: Supplemental Index