THE MECHANISM OF ASYMMETRIC TRANSFORMATION OF 2-SUBSTITUTED ALKANOIC ACIDS VIA CHIRAL OXAZOLINES

Autor: Shibata, Saizo, Matsushita, Hajime, Kaneko, Hajime, Noguchi, Masao, Saburi, Masahiko, Yoshikawa, Sadao
Zdroj: Chemistry Letters; December 1982, Vol. 11 Issue: 12 p1983-1986, 4p
Abstrakt: The mechanism of asymmetric transformation of 2-substituted alkanoic acids via chiral oxazolines was examined using two epimers of (4S)-2-(1-phenylethyl)-4-benzyloxazoline. The transformation in THF was elucidated to be governed by kinetic control, and its process was clarified by measuring the ratio of 13C-labeled lithio oxazolines by 13C NMR.
Databáze: Supplemental Index