| Autor: |
Fujita, Hiroshi, Endo, Rokuro, Aoyama, Akira, Ichii, Takeshi |
| Zdroj: |
Bulletin of the Chemical Society of Japan; June 1972, Vol. 45 Issue: 6 p1846-1852, 7p |
| Abstrakt: |
N,N′-Disubstituted phenylpropiolamidines were synthesized from phenylacetylene and carbodiimides. They were inert toward nucleophiles in a neutral or basic medium, but reactive in an acidic one. They reacted in the presence of hydrogen chloride with hydroxylamine, hydrazine, and arylhydrazines to give 5-N-substituted amino-3-phenylisoxazoles, 5-N-substituted amino-3-phenylpyrazole and 5-N-substituted amino-1-aryl-3-phenylpyrazoles, respectively, by nucleophilic addition followed by cyclization. The reaction mechanism is discussed on the basis of the structures of these heterocyclic compounds. |
| Databáze: |
Supplemental Index |
| Externí odkaz: |
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