Chemical Studies on Tuberactinomycin. XIV. Novel Synthesis of Dl-Capreomycidine

Autor: Wakamiya, Tateaki, Mizuno, Katsutoshi, Ukita, Tatsuzo, Teshima, Tadashi, Shiba, Tetsuo
Zdroj: Bulletin of the Chemical Society of Japan; March 1978, Vol. 51 Issue: 3 p850-854, 5p
Abstrakt: Cyclic guanidino amino acid, capreomycidine, is a component of antituberculous peptides, capreomycin and tuberactinomycin N and O. Its epimer was also found in protease inhibitors, chymostatin and elastatinal. A new synthetic approach to Dl-capreomycidine viaß-hydroxyornithine was studied for the purpose of total synthesis of capreomycidine and epicapreomycidine of natural forms or its hydroxy derivative, tuberactidine.
Databáze: Supplemental Index