STEREOCHEMISTRY OF PETASITENINE, THE CARCINOGENIC ALKALOID FROM PETASITES JAPONICUSMAXIM. AND TRANSFORMATION OF PETASITENINE TO SENKIRKINE

Autor: Yamada, Kiyoyuki, Tatematsu, Hiroshi, Hirata, Yoshimasa, Haga, Masanobu, Hirono, Iwao
Zdroj: Chemistry Letters; October 1976, Vol. 5 Issue: 10 p1123-1126, 4p
Abstrakt: Stereochemistry at C-18 of petasitenine, the carcinogenic alkaloid isolated from Petasites japonicusMaxim. was established by chemical and spectral means: the structure of petasitenine was thus determined completely, which is represented by (1). Transformation of petasitenine (1) into senkirkine (3) was achieved by low valent tungusten complexes.
Databáze: Supplemental Index