Stereoselective Synthesis of β-Phenylserine from Glycine and Benzaldehyde as Mediated by Catalytic Bilayer Membranes, Artificial Vitamin B6-dependent Enzymes

Autor: Kikuchi, Jun-ichi, Takashima, Toru, Nakao, Hidetoshi, Hie, Ken-ichi, Etoh, Hiroshi, Noguchi, Yasuhiro, Suehiro, Kazuaki, Murakami, Yukito
Zdroj: Chemistry Letters; March 1993, Vol. 22 Issue: 3 p553-556, 4p
Abstrakt: The aldolation of glycine with benzaldehyde to yield β-phenylserine was catalyzed by supramolecular assemblies formed with a synthetic peptide lipid, a hydrophobic vitamin B6derivative, and zinc(II) ions in aqueous media under mild conditions. A diastereomeric ratio of the reaction products was much dependent on a size and a phase property of the vesicular catalyst.
Databáze: Supplemental Index