Stereocontrolled Syntheses of Carotenoid Oxidative Metabolites, (-)-Loliolide, (-)-Xanthoxin, and Their Stereoisomers

Autor: Kuba, Masako, Furuichi, Noriyuki, Katsumura, Shigeo
Zdroj: Chemistry Letters; December 2002, Vol. 31 Issue: 12 p1248-1249, 2p
Abstrakt: We achieved the stereocontrolled syntheses of (-)-loliolide, (-)-xanthoxin, and their stereoisomers from (+)- or (-)-3-alkoxy-6-hydroxymethyl-1,1,5-trimethylcyclohexene through the corresponding synand anti-epoxides, respectively, which were obtained by utilizing the highly diastereoselective Sharpless asymmetric epoxidation or mCPBA oxidation.
Databáze: Supplemental Index